Basically there are different settings you can choose under highres for upscaling the images

Algorithim to upscale and make the image more detailed and higher quality

I did a few tests and saw how effective different ones were: There were a lot more tests, but I feel like these are some of the few that were the most effective

Original image (Latent Nearest)

Summary

Latent

Latent

Latent Antialiasing

Latent Antialiasing

Latent Bicubic

Latent Bicubic

Latent Bicubic Antialiased

Latent Bicubic Antialiased

Latent Nearest

Latent Nearest

Latent Nearest Exact

Latent Nearest Exact

None

None

Lanczos

Lanczos

Nearest

Nearest

ESRGAN_4X

ESRGAN_4X

R-ESRGAN 4X+

R-ESRGAN 4X+

R-ESRGAN 4X+ Anime6B

R-ESRGAN 4X+ Anime6B

LDSR

LDSR

ScuNET GAN

ScuNET GAN

ScuNet PSNR

ScuNet PSNR

SwinIR 4X

SwinIR 4X

Lollypop

Lollypop

4XNickelback

4XNickelback

4XFoolhardyRemacri

4XFoolhardyRemacri

4XUltraSharp

4XUltraSharp

4XAnimeSharp

4XAnimeSharp